SaferMix

Information and Warnings about Drug Combinations

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Cannabis×MDMA
⚡︎ Synergistic
Effects amplify or substances synergize with each other. If each substance is not dosed significantly lower than when used individually, overdose with undesirable effects may occur.
○︎ Moderate Risk
This combination typically does not produce additional adverse effects, but the individual substances themselves may carry significant risks.

Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible.

Sources:

[1] TripSit Database of Drug Combinations. https://combo.tripsit.me/