SaferMix by SONAR BERLIN provides brief information about the dangers and risks of combining recreational drugs.
Want to know how psychoactive drugs interact with each other? Enter any 2 substances here to get information on the combination - click the plus symbol to add more.
Interactions between substances are often difficult to predict reliably. Individual factors (e.g., pre-existing conditions, medications, dosage, purity/contaminants, method of consumption) can significantly alter risks and interactions. Combining drugs is therefore generally not recommended, as it usually increases the risks of substance use.
Although considerable effort has been made to avoid errors or misleading information, with the very large number of possible combinations, some content may not be completely correct or up-to-date. Where no scientific sources are cited, information may be based solely on users' experiences. SaferMix should not be used as your sole source of information, but is intended as a supplementary quick reference that makes no claim to completeness.
In acute emergencies, emergency services should be contacted at 112 for immediate on-site medical assistance and/or the responsible poison control center for telemedical advice regarding substance interactions.
Candyflip
⚡︎ Synergistic
Effects amplify or substances synergize with each other. If each substance is not dosed significantly lower than when used individually, overdose with undesirable effects may occur.
○︎ Moderate Risk
This combination typically does not produce additional adverse effects, but the individual substances themselves may carry significant risks.
Users often report that this combination, commonly known as 'candy flipping', makes the LSD experience feel more euphoric, social, or emotionally stable. Some scientific studies suggest that challenging experiences occur less frequently as long as MDMA is taken at a low dose compared to taking LSD alone, while others found no improvement. The overall duration of the experience is extended by the combination.
Sources:
[1] Isabelle Straumann, Laura Ley, Friederike Holze, Anna M. Becker, Aaron Klaiber, Kathrin Wey, Urs Duthaler, Nimmy Varghese, Anne Eckert, Matthias E. Liechti. Acute effects of MDMA and LSD co-administration in a double-blind placebo-controlled study in healthy participants. https://doi.org/10.1038/s41386-023-01609-0
[2] R. Zeifman, H. Kettner, B. Pagni, Austin J. Mallard, Daniel E. Roberts, D. Erritzoe, Stephen Ross, R. Carhart-Harris. Co-use of MDMA with psilocybin/LSD may buffer against challenging experiences and enhance positive experiences. https://doi.org/10.1038/s41598-023-40856-5
