SaferMix

Information and Warnings about Drug Combinations

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Alcohol×Amphetamine
↔️︎ Counteracting
Some effects weaken each other. This may risk consuming more than usual and underestimating the strain on body or mind.
⚠️︎ Caution
This combination creates additional risks and may produce significant adverse effects.

Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol and the stimulant less. Extended release formulations may severely impede sleep, further worsening the hangover.

Sources:

[1] TripSit Database of Drug Combinations. https://combo.tripsit.me/